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Publications



Causes and consequences of chromosome number alterations
  Asymmetric clustering of centrosomes defines the early evolution of tetraploid cells.
       Baudoin N.C., Nicholson J.M., Soto K., Martin O., Chen J., Cimini D. (2020).
       eLife 9, e54565

  Chromosomes missegregated into micronuclei contribute to chromosomal instability by missegregating
       at the next division.

       He B., Gnawali N., Hinman A.W., Mattingly A.J., Osimani A., Cimini D. (2019).
       Oncotarget, 10: 2660-2674.

  Environmental stresses induce karyotypic instability in colorectal cancer cells.
       Tan Z., Chan Y.J.A., Chua Y.J.K., Rutledge S.D., Pavelka N., Cimini D., Rancati G. (2019).
       Molecular Biology of the Cell, 30: 42-55.

  Chromosome segregation: the bigger they come, the harder they fall.
       Baudoin N.C. and Cimini D. (2018).
       Current Biology, 28: R665–R667.

  Selective advantage of trisomic human cells cultured in non-standard conditions.
        Rutledge S.D., Douglas T.A., Nicholson J.M., Vila-Casadesús M., Kantzler C.L., Wangsa D., Barroso-Vilares M.,
        Kale S.D., Logarinho E., and Cimini D. (2016)
        Sci. Rep., 6: 22828.

  Consequences of aneuploidy in sickness and in health.
        Rutledge S.D. and Cimini D. (2016)
        Curr. Opin. Cell Biol., 40: 41-46.

 Aurora A kinase contributes to a pole-based error correction pathway.
       Ye A.A., Deretic J., Hoel C.M., Hinman A.W., Cimini D., WelburnJ.P., and MarescaT.J. (2015)
       Curr. Biol., 25: 1842-1851.

  Chromosome mis-segregation and cytokinesis failure in trisomic human cells.
        Nicholson J.M., Macedo J.C., Mattingly A.J., Wangsa D., Camps J., Lima V., Gomes A.M., Dória S., Ried T.,
        Logarinho E., and Cimini D. (2015)
        eLife, 4: e05068.

  Link between aneuploidy and chromosome instability.
        Nicholson J.M. and Cimini D. (2015)
        Internat. Rev. Cell Mol. Biol., 315: 299-317.

 The mitotic origin of chromosomal instability.
       Bakhoum S.F., Silkworth W.T., Nardi I.K., Nicholson J.M., Compton D.A., and Cimini D. (2014)
       Curr. Biol., 24: R148-149.

 Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment
       and chromosome mis-segregation in cancer cells.

       Silkworth W.T., Nardi I., Scholl L.M., and Cimini D. (2009).
       PloS ONE, 4(8): e6564.

 Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors
       due to merotelic kinetochore orientation.

       Cimini D., Wan X., Hirel C.B., and Salmon E.D. (2006).
       Curr. Biol., 16: 1711-1718.
       [Highlighted in a Dispatch by Zhang and Walczak in Curr. Biol., 16: r677-r678]

 Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells.
       Cimini D., Howell B.J., Maddox P., Khodjakov A., Degrassi F., and Salmon E.D. (2001).
       Journal of Cell Biology, 153: 517-527.
       [Cover Article: Highlighted in "In Brief" by William A. Wells on the same issue of the Journal of Cell Biology]